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Arimidex
is a very new drug developed for the treatment of advanced breast cancer
in women. Specifically, Arimidex is the first in a new class of
third-generation selective oral aromatase inhibitors. It acts by blocking
the enzyme aromatase, subsequently blocking the production of estrogen.
Since many forms of breast cancer cells are stimulated by estrogen, it is
hoped that by reducing amounts of estrogen in the body the progression of
such a disease can be halted. This is the basic premise behind
Nolvadex, except this drug blocks the action and not production of
estrogen. The effects of Arimidex can be quite dramatic to say the least.
A daily dose of one tablet (1 mg) can produce estrogen suppression greater
than 80 % in treated patients. With the powerful effect this drug has on
hormone levels, it is only to be used (clinically) by post-menopausal
women whose disease has progressed following treatment with
Nolvadex (tamoxifen citrate). Side effects like hot flushes and hair
thinning can be present, and would no doubt be much more severe in
pre-menopausal patients.
For
the steroid using male athlete, Arimidex shows great potential. Up to this
point, drugs like Nolvadex and
Proviron have been our weapons against excess estrogen. These drugs,
especially in combination, do prove quite effective. But Arimidex appears
able to do the job much more efficiently, and with less hassle. Its use is
only now catching on, but early reports have been excellent. A single
tablet daily, the same dose use clinically, seems to be all one needs for
an exceptional effect (some even report excellent results with only 1/2
tablet daily). When used with strong, readily aromatizing androgens such
as Dianabol or testosterone, gynecomastia and
water retention can be effectively blocked. In combination with
Proscar (finasteride), we have a great advance. With the one drug
halting estrogen conversion and the other blocking 5-alpha reduction
(testosterone, Methyltestosterone and
Halotestin only), related side effects can be
effectively minimized. Here the strong androgen testosterone could
theoretically provide incredible muscular growth, while at the same time
being as tolerable as nandrolone. Additionally the quality of the muscle
should be greater, the athlete appearing harder and much more defined
without holding excess water.
There are some concerns with using an aromatase inhibitor such as this
during prolonged steroid treatment however. While it will effectively
reduce estrogenic side effects, it will also block the beneficial
properties of estrogen from becoming apparent (namely its effect on
cholesterol values). Studies have clearly shown that when an aromatase
inhibitor is used in conjunction with a steroid such as testosterone,
suppression of HDL (good) cholesterol becomes much more pronounced.
Apparently estrogen plays a role in minimizing the negative impact of
steroid use. Since the estrogen receptor antagonist
Nolvadex is shown not to display an antiestrogenic effect on
cholesterol values, it is certainly the preferred from of estrogen
maintenance for those concerned with cardiovascular health.
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Buy Arimidex :: |
