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Deca Durabolin is one of the most widely used anabolic steroids.
Deca Durabolin's popularity is due to the simple fact that it exhibits
many very favorable properties. Structurally nandrolone is very similar to
testosterone, although it lacks a carbon atom at the 19th position (hence
its other name 19-nortestosterone). The resulting structure is a steroid
that exhibits much weaker androgenic properties than testosterone. Of
primary interest is the fact that nandrolone will not break down to a more
potent metabolite in androgen target tissues. You may remember this is a
significant problem with testosterone. Although nandrolone does undergo
reduction via the same (5-alpha reductase) enzyme that produces DHT from
testosterone, the result in this case is dihydronandrolone. This
metabolite is weaker than the parent nandrolone, and is far less likely to
cause unwanted androgenic side effects. Strong occurrences of oily skin,
acne, body/facial hair growth and hair loss occur very rarely. It is
however possible for androgenic activity to become apparent with this as
any steroid, but with nandrolone higher than normal doses are usually
responsible.
Nandrolone also show an
extremely lower tendency for estrogen conversion. For comparison, the rate
has been estimated to be only about 20% of that seen with testosterone.
This is because while the liver can convert nandrolone to estradiol, in
other more active sites of steroid aromatization such as adipose tissue
nandrolone is far less open to this process. Consequently estrogen related
side effects are a much lower concern with this drug. An antiestrogen is
likewise rarely needed with
Deca Durabolin, gynecomastia only a worry
among sensitive individuals. At the same time water retention is not an
usual concern. This effect can occur however, but is most often related to
higher dosages. The addition of Proviron and/or
Nolvadex should prove sufficient enough to
significantly reduce any occurrence. Clearly
Deca Durabolin is a very safe choice among
steroids. Actually, many consider it to be the best overall steroid for a
man to use when weighing the side effects and results. It should also be
noted that in HIV studies,
Deca Durabolin has been shown not only to
be effective at safely bringing up the lean body weight of patient, but
also to be beneficial to the immune system.
It is of note however that
nandrolone is believed to have some activity as a progestin in the body.
Although progesterone is a c-19 steroid, removal of this group as in
19-norprogesterone creates a hormone with greater binding affinity for its
corresponding receptor. Sharing this trait, many 19-nor anabolic steroids
are shown to have some affinity for the progesterone receptor as well.
This can lead to some progestin-like activity in the body, and may
intensify related side effects. The side effects associated with
progesterone are actually quite similar to those of estrogen, including
negative feedback inhibition of testosterone production, enhanced rate of
fat storage and possibly gynecomastia. Many believe the progestin activity
of
Deca Durabolin notably contributes to
suppression of testosterone synthesis, which can be marked despite a low
tendency for estrogen conversion.
Deca Durabolin is not known as a very
"fast" builder. The muscle building effect of
Deca Durabolin is quite noticeable, but
not dramatic. The slow onset and mild properties of
Deca Durabolin therefore make it more
suited for cycles with a longer duration. In general one can expect to
gain muscle weight at about half the rate of that with an equal amount of
testosterone. A cycle lasting eight to twelve weeks seems to make the most
sense, expecting to elicit a slow, even gain of quality mass. Although
active in the body for much longer,
Deca Durabolin is usually injected once
per week. The dosage for men is usually in the range of 200-600 mg. If
looking to be specific, it is believed that
Deca Durabolin will exhibit its optimal
effect (best gain/side effect ratio) at around 2 mg per pound of
bodyweight/weekly.
Deca Durabolin is also a popular steroid
among female bodybuilders. They take a much lower dosage on average than
men of course, usually around 50 mg weekly. Although only slightly
androgenic, women are occasionally confronted with virilization symptoms
when taking
Deca Durabolin.
As mentioned earlier,
endogenous testosterone levels can be a concern with Deca Durabolin,
especially after long cycles. It is therefore a good idea to incorporate
ancillary drugs at the conclusion of therapy. An estrogen antagonist such
as Clomid or Nolvadex
is therefore commonly used for a few weeks. These both provide a good
level of testosterone stimulation, although they may take a couple of
weeks to show the best effect. HCG injections could
be added for extra reassurance, acting to rapidly restore the normal
ability of the testes to respond to the resumed release of gonadotropins.
For this purpose one could administer three injections of 2500-5000 I.U.,
spaced five days apart. After which point the antiestrogen is continued
alone for a few more weeks in an effort to stabilize the production of
testosterone. Remember to begin the ancillaries after
Deca Durabolin has been withdrawn for a
few weeks, not the first week after the last shot.
Deca Durabolin stays active for quite some
time so the ancillary drugs will not be able to exhibit their optimal
effect when the steroid is still being released into the bloodstream.
The major drawback for
competitive purposes is that in many cases nandrolone metabolites will be
detectable in a drug screen for up to a year (or more) after use. This is
clearly due to the form of administration. Esterified compounds have a
high affinity to stay stored in fatty tissues. While we can accurately
estimate the time frame it will take for a given dose to enter circulation
from an injection site, we cannot know for sure that 100% of the steroid
will have been metabolized at any given point. Small amounts may indeed be
stubborn in leaving fatty tissue, particularly after heavy, longer-term
use. Some quantity of nandrolone decanoate may therefore be left to
sporadically enter into the blood stream many months after use. This
process may be further aggravated when dieting for a show, a time when
body fat sores are being actively depleted (possibly freeing more
steroid). This has no doubt been the cause for many unexpected positives
on a drug screen. The fact that nandrolone has been isolated as the
"hands-off' injectable for the drug tested athlete is most likely due to
its popularity (and therefore common appearance on drug screens).
On the other hand we find
that the use of the oral nandrolone precursors norandrostenedione and
norandrostenediol can allow the drug-tested athlete the benefit of an
injectable nandrolone, without the same risk for a positive result. A
recently published French study makes this possibility very clear. During
this investigation it was shown that trace levels of the nandrolone
metabolites norandrosterone and noretiocholanolone could be found in human
urine up to eight months after a single 50 mg injection of nandrolone
undecanoate. This time frame shrank to only 8 days with norandrostenediol
(50 mg) and norandrostenedione (100 mg).
Those not subject to a drug
screen are likely to find the low water retention and good effect of this
drug favorable for use in pre-contest cutting stacks. A combination of
Deca Durabolin and
Winstrol during the weeks/months leading up to a show for example, is
noted to greatly enhance to look of muscularity and definition. Being an
acceptable anabolic,
Deca Durabolin can also be incorporated
into bulk cycles with good results. The classic
Deca Durabolin and
Dianabol cycle has been a basic for decades, and always seems to
provide excellent muscle growth. A stronger androgen such as
Anadrol or testosterone could also be substituted, producing greater
results. When mixed with
Deca Durabolin, the androgen dosage can be
kept lower than if used alone, hopefully making the cycle more
comfortable. Additionally one may choose to continue
Deca Durabolin for a number of few weeks
after the androgen has been stopped. This will hopefully harden up some of
the bloat produced by the androgen, giving a more quality appearance.
Remember that endogenous testosterone production will not resume during
Deca Durabolin therapy, and ancillaries
are likewise still needed.
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